Daviglus ML, Plassman BL, Pirzada A, et al. Risk Factors and
Preventive Interventions for Alzheimer Disease: State of the Science. Arch
Neurol. 2011;68(9):1185-1190.
·
Four cohort studies
on the association between cognitive engagement and development of AD:
o
In all 4 studies,
participants had normal cognition at baseline, and self-reported frequency of
involvement in specific activities was assessed
o
All 4 studies
showed a somewhat decreased risk of AD associated with greater involvement in
cognitive activities.
Study 1
Verghese J, Lipton RB,
Katz MJ, et al. Leisure activities and the risk of
dementia in the elderly. N Engl J Med. 2003;348(25):2508-2516
PubMed | Link to Article
PubMed | Link to Article
1.
reading,
2.
playing board games,
3.
playing musical instruments, and
4.
dancing.
·
Increased participation in cognitive activities
at base line was associated with reduced rates of decline in memory.
Study 2
Akbaraly TN, Portet F,
Fustinoni S, et al. Leisure activities and the risk of
dementia in the elderly: results from the Three-City study. Neurology. 2009;73(11):854-861
PubMed | Link to Article
PubMed | Link to Article
·
Cognitive activities in which seeking or
processing information plays a central role.
1.
Doing crosswords,
2.
playing cards,
3.
attending organizations,
4.
going to cinema/theater, and
5.
practicing an artistic activity
Study 3
Wilson RS, Mendes De
Leon CF, Barnes LL, et al. Participation in
cognitively stimulating activities and risk of incident Alzheimer
disease. JAMA. 2002;287(6):742-748
PubMed | Link to Article
PubMed | Link to Article
·
7 common activities
that involve information processing as a central component:
1.
viewing television;
2.
listening to radio;
3.
reading newspapers;
4.
reading magazines;
5.
reading books;
6.
playing games such
as cards, checkers, crosswords, or other puzzles; and
7.
going to museums.
Study 4
Wilson RS, Scherr PA,
Schneider JA, Tang Y, Bennett DA. Relation of cognitive
activity to risk of .developing Alzheimer disease. Neurology. 2007;69(20):1911-1920
PubMed | Link to Article
PubMed | Link to Article
·
Level of cognitively stimulating activity in old
age is related to risk of developing dementia.
·
More frequent participation in cognitive
activity was associated with reduced incidence of AD.
·
Frequent cognitive activity was also associated
with reduced incidence of mild cognitive impairment and less rapid decline in
cognitive function.
·
Common activities in which seeking or processing
information played a central role:
1.
reading a newspaper,
2.
playing games like chess or checkers,
3.
visiting a library, or
4.
attending a play
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